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Data Driven Value

Journal Article

Delivering Data Driven Value

Maximizing Data Value for Biopharma through FAIR and Quality Implementation: FAIR Plus Q

Despite considerable progress, the transformative shift from an application-centric to a data-centric perspective, enabled by FAIR implementation, remains very much a work in progress on the ‘FAIR journey’. In this review, we consider use cases for FAIR implementation.

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Webinar

Delivering Data Driven Value

Enhancing Access to Clinical Trial Data for Secondary Use

At the Pistoia Alliance, we are exploring how the FAIRification of such data, along with advanced analytics including AL/ML/NLP powered systems can be used to access/share/reuse patient data from historical clinical trials.

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Webinar

Delivering Data Driven Value

DataFAIRy Bioassay Annotation Pilot Project

In 2020, a team of scientists from AstraZeneca, Bristol Myers Squibb, Novartis, and Roche set forth to find a way to convert unstructured biological assay descriptions into FAIR information objects.

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News Article

Delivering Data Driven Value

Computational approaches to therapeutic antibody design: established methods and emerging trends

Due to their binding versatility, antibodies are currently the largest class of biotherapeutics, with five monoclonal antibodies ranked in the top 10 blockbuster drugs. Computational advances in protein modelling and design can have a tangible impact on antibody-based therapeutic development.

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Toolkit

Core Projects

ABvance Toolkit

The Pistoia Alliance AbVance initiative was focused on two workstreams; (I) advancing the state of the art in antibody complex modelling for drug discovery, and (II) building better predictive models to address ‘developability’ risk

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